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Moderated conference on GMOs in the pipeline, hosted by the FAO Biotechnology Forum in 2012

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Sun, 25 Nov 2012 07:14:53 +0100
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Jim Murray here again to respond to Patrick Monk (Message 32).

All of the species I mentioned are transgenic, although I am not sure that matters given that the regulatory paradigm used in the US considers a genetic construct containing only sequences from the intended target (i.e. all cow sequences in a gene construct for use in a cow) as a transgene.  I am not sure what you mean by the term intra-genic though and how that relates to breeding using an inter-generic cross, say American bison crossed with European cattle to create beefalo (meat from which is available today), or the very many crosses of this type performed regularly during plant breeding. Keep in mind that cultivars like seedless watermelon have been made by inducing triploidy, which essentially gives the plant one additional copy of every watermelon gene and thus would fall into what I think you mean by intra-genic manipulation.

With specific reference to the AquaBounty transgenic Atlantic salmon, studies would indicate that it would not pose a significant risk to the wild stock for a number of reasons, including (1) grower stocks are intended to be all female, triploid fish (which are sterile), (2) in breeding tests artificial streambed environments the transgenic fish are at a mating disadvantage, (3) the proposed growing location is a landlocked facility in Panama, where there are no wild stocks, with a large number of physical and environmental barriers to survival of escaped (or released) fish, and (4)  previous attempts to establish "wild" Atlantic salmon breeding populations in the Pacific ocean have failed. That said, I think other GE fish would need to be looked at on a case by case basis. 

James D. Murray
Professor
Department of Animal Science
Department of Population Health and Reproduction
University of California
One Shields Avenue
Davis CA 95616
United States
Phone: (530) 752-3179
Fax: (530) 752-0175
Email: jdmurray (at) ucdavis.edu

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