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Establishment of a PPR Global Research and Expertise Network (PPR-GREN)

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From:
Paul Rossiter <[log in to unmask]>
Reply To:
Paul Rossiter <[log in to unmask]>
Date:
Fri, 7 Feb 2014 15:58:53 +0000
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Dear Colleagues,

When we first developed PPR Sungri/96 vaccine, during the initial field
evaluation of vaccine we observed goats were better sero-converters than
Sheep. In a study involving more than 500 post-vaccinate sera samples in
each of the species, we observed 98% sero-conversion in goats and 83% in
sheep. Even the VN titer was lesser in sheep than goats (eg., most of the
goats had 1:64 to 1:128 and sheep it was 1:32 to 1:64).

PPR Sungri/96 virus which was used to develop attenuated vaccine was
originally rescued from post-mortem samples from a goat died in the PPR
outbreak.

Does this suggests that we should have separate vaccine candidates for
sheep and goat? I must confess I am not keeping abreast of PPR literature
as I have moved away from PPR research almost 11 years back.

Regards
Srinivas

I hope that several of you will give us your views on this radical idea - moderator 
________________________________
Dr.B.P.Srinivas
Principal Scientist
Indian Veterinary Research Institute (IVRI)
Hebbal, Bangalore-560024
India

Tel:  91-80-23410729 (Work)
Fax: 91-80-23412509

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