Dear Paul

I fully agree that vaccination in the face of an outbreak is appropriate. It will eventually stop the outbreak and I do not know of any untoward effects. As has been pointed out, other options such as stamping out would probably result in a disincentive to report and work against effective control in the longer term.

Regards,

Jeff Mariner

From: Paul Rossiter <[log in to unmask]>
Reply-To: Paul Rossiter <[log in to unmask]>
Date: Wednesday, February 12, 2014 11:18 AM
To: "[log in to unmask]" <[log in to unmask]>
Subject: An important question from Dr M.Afzal in Pakistan

Dear Paul,
 
I would like to request for opinion on vaccination in the face of the outbreak of PPR in the herd.
Dr. M. Afzal
Project Coordinator
FAO Pakistan, Islamabad

In my opinion vaccination of infected and at-risk flocks/herds with good quality PPR vaccine stops transmission very quickly with new clinical cases  ceasing after one or two weeks.  If PPR vaccine is like RP vaccine (an assumption I know) then it provides protective imunity through non-specific mechanisms like interference within 2-3 days, and detectable specific antibody within 5-6 days (VN tests).  More answers please. Moderator.  


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