Dear Moderator,
 
I would like to suggest that our strategy in this vision may contain some of the following points:
        
A: For PPR diagnosis and surveillance:
  • get countries organised in groups per continent (Central Africa, West  Africa, East, etc. for Africa and so on ...)
  • have a programme for each group of countries according to livestock activities (free range, intensive system, etc.)
  • Identify diagnostic labs in each group that can play a role of regional lab based capacity and ability (FAO may a classification under RESOLAB for some countries, no...), and also in each country for national labs
  • attach each regional lab to a ref lab in case of need of declaration of new outbreak in PPR free  countries
  • update capacity buiding for each of these regional and national labs for early and rapid diagnosis of PPR (in labs and on the field): mobile laboratories may be necessary (some lab already have this) for those with long distance to cover, to run rapid field test including maybe ELISA, PCR from nasal swaps and other samples...( the run can be done at least in the closest city to the outbreak site where facilities are available) 
  • put in place a good data collection and fast reporting system (similar to LIMS) in the network (from field to National labs, regionals, and above) 
  • put in place an easy and fast way for sample exportation to regional or Ref labs
  • select lab reagent/consumable producers that can supply at a very low cost, and have a bank of these lab materials in each regional lab for easy distribution incase of need
  • continous molecular epidemiology of PPRV untill eradicated completely
  • apply stamping out during last period when incidence will be nearly zero
B: For Vaccination:
  • do periodic (annual???) massive vaccination in each country (some already sick animals may certainly die...), thermotolerant vaccines will be more prefered due to long distance to cover in some places, and also lack of cold chain facilities in some localities.
  • have PPR vaccine banks in each country for emergency use. Every country? -Moderator
 
Question: According to  work conducted on PPR vaccine, transfered immunity from vaccinated mothers can protect the young for  up to 4 months.... Is that correct??? Yes, and maybe  longer sometimes perhaps 6  to even 8 months in some individuals.- Moderator.Anyway, we need to define when and how to get these young sheep and goats vaccinated regularly without waiting for the (annual ???) campaign. I fully agree - and this is precisely the kind of challenge that the proposed PPR-GREN could help with by encouraging people to share their experience with different and innovative vaccine delivery mechanisms as we try to immunize the younger animals where the disease is constantly or frequently present -Moderator. 
 
Question: What about wildlife animals that are susceptible to PPR? Can we get them vaccinated??? How to control them?  At present I don't think we can vaccinate wildlife populations -  individuals maybe if we know that the vaccine is safe in the species in question. But I don't think we want to vaccinate them.  At present there is no evidence that they maintain PPR virus (possibly they do somewhere, somehow and we must look closely into this issue to rule it out) but they do provide a sentinel population for circulating virus in neighbouring populations of small ruminants. Just as unvaccinated wildlife could help us against RP  wildlife surveillance may helped against PPR.  I expect others to have some additional comments here -Moderator.   
 
Best regards
 
Wade
 
Dr Abel WADE
Director of LANAVET annex
Yaoundé-Cameroon
Consultant
Animal Production and Health Laboratory
Joint FAO/IAEA’S Laboratory, Seibersdorf
Nuclear Sciences and Application
International Atomic Energy Agency (IAEA)
A-1400 Vienna, Austria
Tel: +43 67 69 71 52 98 (Mobile)
E.mail.
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