With thanks to Dr Rabindra Singh for this response to the moderator's question following Dr Singh's contribution on the availability of vaccine and its use in India (22 Feb 2013). Moderator.



Dear Paul, 
We have observation of more than 95% reduction in outbreaks in two of the Indian states, which adapted this strategy of vaccination honestly. However, to reach to 0% occurrence definately we need repeated carpet/ mass vaccination campaigns. But, the approach will help us in creating an awareness to go for successfull mass vaccinations with higher acceptability (seing is believing) amongst the public. 
regards,
R.P.Singh 
 
----- Original Message -----
>From: Paul Rossiter
>Sent: 02/22/14 01:42 PM
>To: [log in to unmask]
>Subject: From Dr Rabindra Singh on the availability of vaccine and its use in India. Plus Moderator's comment.  
>Dear Paul & All,
>
>Unlike inactivated vaccines (FMD, Rabies), upscaling of PPR vaccine is not a problem with the industries under Public-Private partnership.
>Further there may be two ways to economize vaccine use in case of PPR. Ist is focussed vaccination in high risk population as suggested by you. IInd is strategic vaccination. Ist one may be suitable for the countries which have low capacity for vaccine production, while IInd strategy could be adapted by the countries that have good internal capacity for vaccine production. For me strategic vaccination is  mass vaccination (Ist year)-followed by vaccination of new born and unvaccinated (IInd year)-followed by vaccination of unvaccinated and newborn (IIIrd year) in a cycle of three years, as the vaccine produces life long Immunity (at least for three years).  This cycle can be repeated again. Here in this case cumulative vaccinations over a period of preceeding three years are more important for building a good herd/flock immunity than that of annual vaccinations. Government of India has significantly reduced the PPR occurence (about 70%) by following
 this strategy of vaccination. This also helps us to use the vaccine efficiently when capcity for PPR vaccination is limited. The strategy adapted is free vaccination by government, with some limited registation charges from the owners of goats and sheep.
>kind regards,
>R.P.Singh
>
>Dr. R.P.Singh, 
>Principal Scientist, Division of Biological Products,
>Indian Veterinary Research Institute, Izatnagar, 
>Bareilly-243 122 (Uttar Pradesh),
>India
>
>Alternate email: [log in to unmask]
>Mobile:+91-9412360917 
>
>
>Dear Dr Singh,  
>
>This 70% reduction in occurence (prevalence?) is encouraging. But do you think this strategic vaccination you are using will be sufficient to continue reducing the occurence of PPR from 30% to 0% and elimimate the infection? Or may you need some other strategy/tactics for the final endgame? - regards, moderator. 
>

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